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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE4A
All Species:
35.15
Human Site:
S74
Identified Species:
55.24
UniProt:
Q14139
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14139
NP_004779.2
1066
122561
S74
E
I
S
R
S
F
R
S
Q
Q
E
I
C
E
Q
Chimpanzee
Pan troglodytes
XP_001161169
1066
122495
S74
E
I
S
R
S
F
R
S
Q
Q
E
I
C
E
Q
Rhesus Macaque
Macaca mulatta
XP_001097812
1067
122494
S74
E
I
S
R
S
F
R
S
Q
Q
E
I
C
E
Q
Dog
Lupus familis
XP_850081
1066
122542
S74
E
I
S
R
S
F
R
S
Q
Q
E
I
C
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES00
1173
133285
R137
E
V
D
E
N
D
R
R
E
K
R
S
L
S
D
Rat
Rattus norvegicus
Q6P7A2
1066
122361
T74
E
I
S
R
S
F
R
T
H
Q
E
M
C
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026081
1074
123247
S75
E
I
S
R
S
F
R
S
Q
R
E
L
C
E
Q
Frog
Xenopus laevis
NP_001084506
1072
122544
S73
E
I
S
R
S
F
R
S
Q
Q
E
I
C
E
Q
Zebra Danio
Brachydanio rerio
XP_001922961
1078
122949
S77
E
I
S
R
S
F
R
S
R
Q
E
L
C
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609060
993
113046
A93
E
M
A
M
E
R
R
A
M
R
Y
L
K
G
A
Honey Bee
Apis mellifera
XP_393070
965
109934
C71
K
I
N
N
Q
V
N
C
L
L
G
D
I
L
G
Nematode Worm
Caenorhab. elegans
Q09349
980
113212
T73
S
N
I
A
E
I
I
T
K
F
V
L
L
S
Q
Sea Urchin
Strong. purpuratus
XP_786748
942
107668
V77
E
D
M
P
P
K
C
V
F
L
V
D
M
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LF41
1038
117510
S98
D
E
S
K
K
I
Q
S
M
K
D
K
N
L
R
Baker's Yeast
Sacchar. cerevisiae
P54860
961
109887
Q70
C
F
R
R
N
Q
Q
Q
K
R
I
T
K
N
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
98.6
N.A.
24.6
97
N.A.
N.A.
87.7
79.7
76.7
N.A.
33.1
36.5
22.9
32.7
Protein Similarity:
100
100
98.5
99.4
N.A.
45.2
99
N.A.
N.A.
94.3
90.8
87.4
N.A.
51.3
54.5
42.5
52.2
P-Site Identity:
100
100
100
100
N.A.
13.3
80
N.A.
N.A.
86.6
100
86.6
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
40
93.3
N.A.
N.A.
100
100
100
N.A.
46.6
20
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
0
0
7
0
0
0
0
0
7
7
% A
% Cys:
7
0
0
0
0
0
7
7
0
0
0
0
54
0
0
% C
% Asp:
7
7
7
0
0
7
0
0
0
0
7
14
0
0
14
% D
% Glu:
74
7
0
7
14
0
0
0
7
0
54
0
0
54
0
% E
% Phe:
0
7
0
0
0
54
0
0
7
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
60
7
0
0
14
7
0
0
0
7
34
7
0
0
% I
% Lys:
7
0
0
7
7
7
0
0
14
14
0
7
14
0
7
% K
% Leu:
0
0
0
0
0
0
0
0
7
14
0
27
14
14
0
% L
% Met:
0
7
7
7
0
0
0
0
14
0
0
7
7
0
0
% M
% Asn:
0
7
7
7
14
0
7
0
0
0
0
0
7
7
0
% N
% Pro:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
7
14
7
40
47
0
0
0
0
60
% Q
% Arg:
0
0
7
60
0
7
67
7
7
20
7
0
0
0
7
% R
% Ser:
7
0
60
0
54
0
0
54
0
0
0
7
0
14
0
% S
% Thr:
0
0
0
0
0
0
0
14
0
0
0
7
0
0
0
% T
% Val:
0
7
0
0
0
7
0
7
0
0
14
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _